The Heat Insulation Solar Glass (HISG) which was developed by National Taiwan University of Science and Technology (NTUST) is very unique in the world due to it can generate solar power to supply all the energy consumption from cooling and heating system and still remain some power to feed back into grid. There is no possibility for any other glass in the world to reach this target. The reflection of the heat insulation reflection film can enhance the solar power generation and heat insulation simultaneously to gain more renewable energy and reduce more energy consumption from cooling and heating system. The test result of two glass houses showed that the HISG house can generate enough energy to supply the cooling energy consumption and still have some electricity could be send back to grid, meanwhile, the normal double glazing house needed power from grid to supply the cooling consumption. In additions, according to a computer simulation on the energy saving of a 26m x 26 m skylight on a 4 m high building in London and Abu Dhabi, the HISG can save 173,993 kWh and 256,512 kWh and decrease CO2 of 121,795 and 179,558 kg respectively while compared with normal glass. The HISG is very unique in the world for zero energy buildings in the future. The application of HISG includes skylight, vertical window and façade of buildings. For the issue of zero energy buildings, the HISG could be the best choice due to it satisfies the requirement of higher renewable energy supply and lower energy consumption from cooling and heating system. On the aspect of design for a sustainable building, the HISG could be applied not only in the stage of passive design as powerful insulation construction materials and also in the stage of active solution due to its higher renewable energy supply.