One of the best carbon capture methods is alcohol amine solution. This article uses Aspen Plus software to simulate the capture of CO2 in flue gas by MDEA solution absorbent. Investigations were conducted into the impacts of operating factors on the rate of absorption and regenerated use of energy, including flue gas inlet temperature, desorption tower pressure, reflux ratio, lean CO2 load, rich feed position, and temperature. and optimal process parameters were obtained. The simulation results show that various operating parameters have an impact on the rate of absorption and the energy used for regeneration. The absorption tower's typical forthcoming flue gas temperature is 40 oC, the lean liquid CO2 load is 0.18 mol/mol, the reflux ratio is 0.8, The rich fluid intake location is a second plate down from the top of the desorption tower, with a temperature for inlet of 95 oC and a pressure of 2.2 bar. Compared with before optimization, the CO2 absorption rate of the system increases from 84.1% to 94.4%, the regeneration energy consumption increases from 3.29 GJ/t CO2 to 3.56 GJ/t CO2, and the regeneration energy consumption only increases by 0.27 GJ/t CO2.